I have been testing out Mac Os in a virtual machine on my pc, specifically to see how i could compile mac native builds of the Playdate games i created. There were already windows builds and now also Mac builds as i've got the build process working using github actions and my playdate SDL2 Api reimplementation. So now you can download this game also as a native mac (.app) binary.

If you download and run the game using the mac itch.io client there do not seem to be any problems.
However if you download the archive manually, you will need to extract it first. Mac Os will also complain about security things saying it can't open the app and it should be moved to the recycle bin, when double clicking it. You should right click the game's app file and choose open then. It will complain one more time but there will be an option to open the game. Also you should move the game's app to the Applications section of Mac Os or at least some other folder than the folder where you extracted it or you may encounter issues, due to apple translocation functionality and read only file system in such situations. This is normal for apps on Mac Os apparently. 

The Game is compiled as an intel x64 binary on Mac Os 12, but i tested it in Mac Os 14 in my vm and it worked fine. 
Someone also tested the game on a real mac using apple silicon cpu's (M1, M2, M3 ...) and it ran fine as well although the intel code will be transpiled to arm code while the application is running. but this seemed to work fine as well.